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	Provedor de dados BJMBR (2) Autor Sichero,L. (2) Villa,L.L. (2) Betiol,J. (1) Palavra-chave Human papillomavirus (2) Oncogenic potential (2) Cervical cancer (1) DNA sequencing (1) Epidemiology (1) Head and neck cancer (1) Immunity (1) Viral prevalence (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2013 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Epidemiological and functional implications of molecular variants of human papillomavirus BJMBR Sichero,L.; Villa,L.L.. Human papillomavirus genomes are classified into molecular variants when they present more than 98% of similarity to the prototype sequence within the L1 gene. Comparative nucleotide sequence analyses of these viruses have elucidated some features of their phylogenetic relationship. In addition, human papillomavirus intratype variability has also been used as an important tool in epidemiological studies of viral transmission, persistence and progression to clinically relevant cervical lesions. Until the present, little has been published concerning the functional significance of molecular variants. It has been shown that nucleotide variability within the long control region leads to differences in the binding affinity of some cellular transcriptional... Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papillomavirus; DNA sequencing; Oncogenic potential; Cervical cancer; Immunity; Epidemiology. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600002 Impact of HPV infection on the development of head and neck cancer BJMBR Betiol,J.; Villa,L.L.; Sichero,L.. Human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is considered to be a distinct clinical entity with better prognosis than the classical tobacco- and alcohol-associated tumors. The increasing incidence of this neoplasia during the last decades highlights the need to better understand the role of HPV in the development of these cancers. Although the proportion of HNSCC attributed to HPV varies considerably according to anatomical site, overall approximately 25% of all HNSCC are HPV-DNA positive, and HPV-16 is by far the most prevalent type. In this review we discuss the existing evidence for a causal association between HPV infection and HNSCC at diverse anatomical head and neck subsites. Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papillomavirus; Oncogenic potential; Head and neck cancer; Viral prevalence. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000300217 Registros recuperados: 2 Primeira ... 1 ... Última

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